GT SifrARN (Structure, Integration, Function, and Reactivity of RNAs)

The SifrARN Thematic Group is a community of researchers interested in the fundamental aspects of RNA biogenesis and degradation mechanisms, RNA structure, and RNA functions in both prokaryotes and eukaryotes, as well as in new RNA-related technologies and applications, particularly in the biomedical field.

RNAs play key roles in regulating gene expression in all living organisms and are also used as biomarkers and therapeutic targets in numerous pathologies, including cancer and infectious diseases. The wide variety of RNA functions and mechanisms of action relies on their structures, modifications, and interactions with proteins.
With the largest number of registered members, the SifrARN WG is the largest working group within the SFBBM. It has been meeting every two years since 1996 for a 2–3 day conference, which has been increasingly successful. This event is the most important in France dedicated to the broad field of RNA research.

Who leads the group?

A team committed to serving the scientific community.

Cyril Bourgeois

Responsable et relation SFBBM

cyril.bourgeois@inserm.fr

Reynald Gilet

Responsable SIFRARN 2026

reynald.gillet@univ-rennes.fr

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The thematic groups are open to SFBBM members who are motivated by scientific exchange.

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The SFBBM thematic groups

Spaces for exchange and collaboration among researchers to advance research in biochemistry and molecular biology.

GT Archaea

Bringing together biochemists and molecular biologists interested in the study of archaea, a distinct domain of life, with unique adaptive and evolutionary properties.

GT Cellular proteolysis

Study protein degradation in cells, whether for renewal, signaling, or the removal of damaged proteins.

GT Enzymes

Exploring all aspects of enzymes, from the most fundamental (structure, mechanism, regulation) to the most applied (engineering, biocatalysis, enzymopathies).

GT Metabolism

Decipher metabolic pathways, their regulation, and their dysregulation, particularly in diseases.

GT SifrARN

Characterize the biogenesis, degradation, structure, and functions of RNAs in prokaryotes and eukaryotes.

GT Synthetic Biology

Design and construct new or redesigned biological systems (or components).

GT Education

Building a community of teachers and researchers committed to advancing teaching practices in biochemistry (lessons learned, tool sharing, improved learning, …).

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