GT Synthetic Biology

This Thematic Group brings together two disciplines: synthetic biology and systems biology.

Synthetic Biology encompasses two complementary approaches to understanding and manipulating living systems. On the one hand, it involves the deconstruction and reduction of complex biological systems and phenomena into simple elements (“top-down” approaches). On the other hand, it focuses on the design and construction of new biological systems from these well-characterized components (“bottom-up” approaches).
Systems Biology, for its part, provides a multidisciplinary and multi-scale view of how living organisms function, with the aim of understanding the regulatory networks and interactions that govern an organism as a whole. In this way, Systems Biology proposes principles that explain the logic of living systems, while Synthetic Biology tests and applies these principles using engineering methods.
These two disciplines are therefore in continuous interaction, mutually enriching one another. Together, they enable the acquisition of fundamental knowledge about how biological systems function, as well as the development of concepts and tools for biotechnologies.

Who leads the group?

A team committed to serving the scientific community.

Agathe Urvoas

I2BC- Gif sur Yvette

Olivier Borkowski

Micalis, Jouy-en-Josas

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The thematic groups are open to SFBBM members who are motivated by scientific exchange.

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Spaces for exchange and collaboration between researchers, to advance research in biochemistry and molecular biology.

Spaces for exchange and collaboration among researchers to advance research in biochemistry and molecular biology.

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Study protein degradation in cells, whether for renewal, signaling, or the removal of damaged proteins.

GT Enzymes

Exploring all aspects of enzymes, from the most fundamental (structure, mechanism, regulation) to the most applied (engineering, biocatalysis, enzymopathies).

GT Metabolism

Decipher metabolic pathways, their regulation, and their dysregulation, particularly in diseases.

GT SifrARN

Characterize the biogenesis, degradation, structure, and functions of RNAs in prokaryotes and eukaryotes.

GT Synthetic Biology

Design and construct new or redesigned biological systems (or components).

GT Education

Building a community of teachers and researchers committed to advancing teaching practices in biochemistry (lessons learned, tool sharing, improved learning, …).

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